Disease animal model
IPHASE establishes animal models of various diseases according to customer requirements, explores the mechanism of disease occurrence and development, provides clues and basis for the research and development of new drugs for prevention and treatment of diseases, and customizes animal models of various systemic diseases, such as cardiovascular, respiratory, digestive, hematopoiesis, urinary, reproductive, endocrine, neurological, motor, etc.
Establish tumor cell line based xenotransplantation tumor (CDX) model and humanized tumor transplantation (PDX) model (breast cancer, leukemia, lymphoma, etc.), and develop and implement anti-tumor drug screening research according to customer requirements.
The animal model of diabetes was established by means of chemical drug (streptozotocin STZ) induction and high-fat feed, and the technical services of efficacy evaluation and pharmacological mechanism analysis were provided.
Establish models of inflammation (xylene), pain (acetic acid writhing), fever (induced by dry yeast), etc., to evaluate the anti-inflammatory, analgesic, antipyretic and other effects of drugs.