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Biological Sample Analysis
Therapeutic drug concentration monitoring
Therapeutic Drug Monitoring (TDM) refers to the determination of drug concentrations in blood and other body fluids and the acquisition of relevant parameters based on pharmacokinetic principles and modern analytical methods, which provides the basis for scientific, individualized and rational clinical use of drugs, so as to improve drug efficacy and avoid drug poisoning reactions.
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● Cardiac glycoside: digoxin, digoxin
● Antiepileptic drugs: phenytoin sodium, ethiramine, carbamazepine, promidone, sodium valproate, phenobarbital
● Anti-arrhythmic drugs: amiodarone, procaine amine, quinidine, lidocaine, etc
● β- Receptor blockers: propranolol, atenolol, metoprolol, etc
● Antiasthmatic drugs: theophylline, aminophylline
● Antipsychotic drugs: risperidone, olanzapine, quetiapine
● Antidepressants: amitriptyline, imipramine, desmopramine, doxepin
● Antimanic drug: lithium carbonate
● Immunosuppressive drugs: cyclosporine A, tacrolimus, sirolimus, mycophenolic acid, etc
● Antibiotics: aminoglycosides, vancomycin, chloramphenicol, etc
● Antimalignant drugs: methotrexate, cyclophosphamide, doxorubicin, etc